SCHEMBL27660465

SCHEMBL27660465

COC(C(=O)c1ccccc1)=C(OC)c1ccc(OC)c(OC)c1OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
PKM P14618 1/20 0.46
MAPT P10636 3/20 0.44
KDM4E B2RXH2 2/20 0.44
ALOX15 P16050 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NPC1 O15118 4/20 0.43
RAB9A P51151 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CASP3 P42574 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
ATM Q13315 1/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27660424 0.89 NPC1 (0.49) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL27680429 0.88 ATM (0.47) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL27888985 0.82 MAPT (0.51) ALDH1A1MEN1KMT2APKMMAPT
SCHEMBL5182345 0.82 ALDH1A1 (0.48) ALDH1A1MEN1KMT2APKMMAPT
SCHEMBL2446110 0.77 MAPT (0.66) ALDH1A1MEN1KMT2APKMMAPT
SCHEMBL30023422 0.77 MAPT (0.66) ALDH1A1MEN1KMT2APKMMAPT
SCHEMBL29625356 0.77 TSHR (0.52) KMT2AMAPTRAB9AATMLMNA
SCHEMBL1590640 0.74 ALDH1A1 (0.49) ALDH1A1MEN1KMT2APKMMAPT
SCHEMBL6129286 0.74 CYP1A1 (0.45) ALDH1A1MEN1KMT2APKMMAPT
SCHEMBL3789792 0.74 NPC1 (0.50) ALDH1A1MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1990482-A Flavanonol compounds and their production method and use ZHEJIANG HISUN NATURELITE PHAR (CN) 2007-07-04 CN claimed
CN-1990482-B Flavanonol compounds and their production method and use ZHEJIANG HISUN PHARM CO LTD 2010-12-08 CN disclosed
CN-1990482-A Flavanonol compounds and their production method and use ZHEJIANG HISUN NATURELITE PHAR (CN) 2007-07-04 CN disclosed