Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dl-Phenylalanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL12483330 | 0.96 | SLC7A5 (0.45) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL12483321 | 0.96 | SLC7A5 (0.45) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL27321955 | 0.96 | SLC7A5 (0.45) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL9802538 | 0.94 | REN (0.45) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL28801804 | 0.94 | ALPI (0.43) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL21899698 | 0.92 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL21899697 | 0.92 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| Tyrosine SCHEMBL12497096 | 0.91 | SLC7A5 (0.51) | SLC7A5ALPIPKMPTGS1XIAP | |
| Tyrosine SCHEMBL17728294 | 0.91 | SLC7A5 (0.51) | SLC7A5ALPIPKMPTGS1XIAP | |
| Tyrosine SCHEMBL12497090 | 0.91 | SLC7A5 (0.51) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1889974-A | Oligopeptides as coating material for medical products | HEMOTEQ GMBH (DE) | 2007-01-03 | — | — | CN | claimed |
| CN-116735752-A | Method for detecting content of bioactive peptide in wine | 宜宾五粮液股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-1889974-B | Oligopeptides as coating material for medical products | HEMOTEQ GMBH | 2012-08-29 | — | — | CN | disclosed |
| CN-1889974-A | Oligopeptides as coating material for medical products | HEMOTEQ GMBH (DE) | 2007-01-03 | — | — | CN | disclosed |