Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 7/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28751263 | 0.97 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Butyl Alcohol SCHEMBL27269584 | 0.97 | — | — | |
| Piperazine SCHEMBL27487127 | 0.92 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| 1-Hexanol SCHEMBL26102045 | 0.89 | LMNA (0.68) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Butyl Alcohol SCHEMBL27831587 | 0.89 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| 1-Hexanol SCHEMBL28925761 | 0.87 | LMNA (0.65) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Piperidine SCHEMBL27257161 | 0.87 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Cetostearyl Alcohol SCHEMBL10378874 | 0.86 | LMNA (0.72) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| 1-Hexanol SCHEMBL28922621 | 0.85 | LMNA (0.62) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Piperidine SCHEMBL28153478 | 0.85 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113371736-A | Method for recycling sodium chloride and sodium sulfate mixed waste salt | 浙江红狮环保股份有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-87104499-A | Novel alginic acid esters | — | 1988-04-06 | — | — | CN | claimed |
| CN-119137172-A | Process and catalyst for hydrogen-mediated anionic copolymerization of conjugated dienes and liquid copolymers thereof | 雅宝公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-113371736-A | Method for recycling sodium chloride and sodium sulfate mixed waste salt | 浙江红狮环保股份有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-110198932-A | Alkanolamine, anti-friction agent and lubricant oil composite | 东曹株式会社 | 2019-09-03 | — | — | CN | disclosed |
| CN-1953747-A | Diphenyl-indol-2-on compounds and their use in the treatment of cancer | TOPOTARGET AS (DK) | 2007-04-25 | — | — | CN | disclosed |