Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Racemethionine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BHMT | Q93088 | 4/20 | 0.35 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methionine SCHEMBL8465848 | 0.93 | MEN1 (0.38) | MEN1KMT2ABHMTBHMT2FNTA | |
| Racemethionine SCHEMBL27639976 | 0.92 | MEN1 (0.42) | MEN1KMT2ABHMTBHMT2LMNA | |
| Racemethionine SCHEMBL4275749 | 0.92 | MEN1 (0.47) | MEN1KMT2ABHMTBHMT2LMNA | |
| Racemethionine SCHEMBL23924535 | 0.92 | MEN1 (0.47) | MEN1KMT2ABHMTBHMT2LMNA | |
| Methionine SCHEMBL4275752 | 0.92 | MEN1 (0.47) | MEN1KMT2ABHMTBHMT2LMNA | |
| Racemethionine SCHEMBL9784232 | 0.90 | MEN1 (0.44) | MEN1KMT2ABHMTBHMT2LMNA | |
| Methionine SCHEMBL6248021 | 0.90 | MEN1 (0.44) | MEN1KMT2ABHMTBHMT2LMNA | |
| Leucine SCHEMBL196371 | 0.87 | MEN1 (0.34) | MEN1KMT2AFNTAFNTBPGGT1B | |
| Racemethionine SCHEMBL23924542 | 0.87 | MEN1 (0.43) | MEN1KMT2ABHMTBHMT2LMNA | |
| Methionine SCHEMBL3091904 | 0.87 | MEN1 (0.43) | MEN1KMT2ABHMTBHMT2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1889974-A | Oligopeptides as coating material for medical products | HEMOTEQ GMBH (DE) | 2007-01-03 | — | — | CN | claimed |
| CN-1889974-B | Oligopeptides as coating material for medical products | HEMOTEQ GMBH | 2012-08-29 | — | — | CN | disclosed |
| CN-1889974-A | Oligopeptides as coating material for medical products | HEMOTEQ GMBH (DE) | 2007-01-03 | — | — | CN | disclosed |