SCHEMBL27660936

SCHEMBL27660936

O=C(Cl)N1C=CC=CC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31356399 0.73
SCHEMBL4073685 0.71
SCHEMBL28673682 0.69 TSHR (0.32)
SCHEMBL27414399 0.69 LMNA (0.32)
SCHEMBL5672376 0.69
SCHEMBL1701374 0.69
SCHEMBL28613075 0.69 SMN1; SMN2 (0.32)
Hydrogen Sulfide SCHEMBL27522910 0.69
Water SCHEMBL8221741 0.69
Water SCHEMBL27524007 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1972932-A Compounds and methods for treating dyslipidemia LILLY CO ELI (US) 2007-05-30 CN disclosed
CN-1863778-A Compounds and methods for treating dyslipidemia LILLY CO ELI (US) 2006-11-15 CN disclosed