SCHEMBL4073685

SCHEMBL4073685

O=C(O)N1C=CC=CC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL27522910 0.97
Water SCHEMBL8221741 0.97
Water SCHEMBL27524007 0.97
SCHEMBL27640180 0.87 LMNA (0.30)
SCHEMBL31356399 0.76
SCHEMBL2338031 0.72
SCHEMBL5672376 0.71
SCHEMBL1701374 0.71
SCHEMBL28613075 0.71 SMN1; SMN2 (0.32)
SCHEMBL27660936 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1972932-A Compounds and methods for treating dyslipidemia LILLY CO ELI (US) 2007-05-30 CN claimed
EP-1761522-A1 COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA ELI LILLY AND COMPANY (US) 2007-03-14 EP claimed
CN-1863778-A Compounds and methods for treating dyslipidemia LILLY CO ELI (US) 2006-11-15 CN claimed
WO-2006002342-A1 COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA ELI LILLY AND COMPANY (US) 2006-01-05 WO claimed
CN-1056878-A 2-substituted alkyl-3-carboxycarbapenems as antibiotics and process for their preparation AMERICAN CYANAMID CO (US) 1991-12-11 CN claimed
JP-57117743-A None JP disclosed
WO-2026101924-A1 KRAS MODULATORS ALTEROME THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-12466842-B2 Substituted pyrido [4,3-d]pyrimidines as KRAS modulators ALTEROME THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
EP-4577549-A1 COMPOUNDS AND METHODS FOR MODULATING HER2 Iambic Therapeutics, Inc. (US) 2025-07-02 EP disclosed
WO-2025124459-A1 TRICYCLIC FUSED HETEROCYCLIC PDE3/4 DUAL INHIBITOR, AND PREPARATION AND USE THEREFOR 石家庄以岭药业股份有限公司 2025-06-19 WO disclosed
CN-119462659-A Bridged tricyclic carbamoyl pyridone compounds and pharmaceutical uses thereof 吉利德科学公司 2025-02-18 CN disclosed
CN-113874079-B Bridged tricyclic carbamoyl pyridone compounds and pharmaceutical uses thereof 吉利德科学公司 2024-11-08 CN disclosed
WO-2006029154-A2 NOVEL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2006-03-16 WO disclosed
WO-2006002342-A1 COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA ELI LILLY AND COMPANY (US) 2006-01-05 WO disclosed
CN-1649879-A Non-steroidal progesterone receptor modulators AKZO NOBEL NV (NL) 2005-08-03 CN disclosed
WO-2005037796-A1 COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA ELI LILLY AND COMPANY (US) 2005-04-28 WO disclosed
EP-0297661-A1 [(Bicyclic heterocyclyl)methyl and -hetero] substituted hexahydro-1H-azepines and pyrrolidines JANSSEN PHARMACEUTICA N.V. (BE) 1989-01-04 EP disclosed
EP-0282133-A2 1-alkyl substituted benzimidazole derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1988-09-14 EP disclosed
CN-85106982-A bicyclic compound and preparation method thereof 1987-05-20 CN disclosed
JP-S57117743-A COLLECTOR FOR USE IN SOLAR ENERGY UTILIZING SYSTEM DAINIPPON INK & CHEM INC 1982-07-22 JP disclosed