Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27916316 | 0.84 | CYP1A2 (0.52) | L3MBTL1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL27640139 | 0.83 | PLAAT5 (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 | |
| SCHEMBL7749862 | 0.82 | KMT2A (0.46) | KMT2AL3MBTL1SMN1; SMN2HPGDALPL | |
| SCHEMBL27660855 | 0.80 | HPGD (0.49) | KMT2APLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL27640142 | 0.79 | KDM4E (0.40) | KMT2AL3MBTL1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8665145 | 0.75 | MAOB (0.48) | KMT2ASMN1; SMN2ALDH1A1MEN1CYP2C9 | |
| SCHEMBL10058715 | 0.74 | MEN1 (0.66) | KMT2AL3MBTL1SMN1; SMN2HPGDALPL | |
| SCHEMBL8680610 | 0.74 | CES1 (0.45) | KMT2AL3MBTL1SMN1; SMN2HPGDALPL | |
| SCHEMBL27640143 | 0.73 | RAB9A (0.50) | KMT2AL3MBTL1SMN1; SMN2HPGDGAA | |
| SCHEMBL6974619 | 0.72 | PLAAT5 (0.65) | KMT2AL3MBTL1PLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282043-B | Congenital agyria therapeutic agent | OSAKA CITY UNIVERSITY (JP) | 2015-09-30 | — | — | CN | disclosed |
| CN-103282043-A | Lissencephaly therapeutic agent | UNIV OSAKA CITY | 2013-09-04 | — | — | CN | disclosed |
| CN-100463901-C | Alpha-ketoamide derivative, and production method and use thereof | SENJU PHARMA CO (JP) | 2009-02-25 | — | — | CN | disclosed |
| CN-1890210-A | Alpha-ketoamide derivatives, method for producing same and use thereof | SENJU PHARMA CO (JP) | 2007-01-03 | — | — | CN | disclosed |