Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 3/20 | 0.34 |
| ▸ | ADH1A | P07327 | 3/20 | 0.34 |
| ▸ | ADH1C | P00326 | 2/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27759367 | 0.78 | — | — | |
| SCHEMBL769923 | 0.77 | ADH1B (0.59) | KDM4EALDH1A1POLBKDM1AADH1B | |
| SCHEMBL3172838 | 0.76 | — | — | |
| SCHEMBL27758272 | 0.74 | — | — | |
| SCHEMBL3173876 | 0.74 | ADH1B (0.59) | KDM4EALDH1A1ADH1BADH1AADH1C | |
| SCHEMBL23845317 | 0.74 | ADH1B (0.59) | KDM4EALDH1A1ADH1BADH1AADH1C | |
| SCHEMBL21422780 | 0.73 | KDM1A (0.47) | ALDH1A1POLBKDM1ANCF1KAT2B | |
| SCHEMBL28481551 | 0.72 | KDM1A (0.41) | POLBKDM1AADH1BADH1ANCF1 | |
| SCHEMBL6902018 | 0.72 | PKM (0.40) | KDM4EALDH1A1POLB | |
| SCHEMBL14128700 | 0.72 | POLB (0.39) | KDM4EALDH1A1POLBKDM1ANCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930144-A | 3-'4-heterocyclyl -1,2,3,-triazol-1-yl!-n-aryl-benzamides as inhibitors of the cytokines production for the treatment of chronic inflammatory diseases | BOEHRINGER INGELHEIM PHARMA (US) | 2007-03-14 | — | — | CN | disclosed |