Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.30 |
| ▸ | CA1 | P00915 | 3/20 | 0.30 |
| ▸ | CA2 | P00918 | 3/20 | 0.30 |
| ▸ | CA7 | P43166 | 3/20 | 0.30 |
| ▸ | CA9 | Q16790 | 3/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27868546 | 0.81 | NR1H2 (0.36) | BCHE | |
| SCHEMBL5771784 | 0.74 | TSHR (0.39) | P2RX4BCHECA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL27640178 | 0.73 | TSHR (0.37) | P2RX4BCHECA12CA1CA2 | |
| SCHEMBL6414618 | 0.67 | TSHR (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27209677 | 0.66 | TSHR (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19347183 | 0.63 | TSHR (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23585326 | 0.61 | TSHR (0.32) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5552219 | 0.61 | KDM4E (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19350785 | 0.61 | ALDH1A1 (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27655284 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863778-A | Compounds and methods for treating dyslipidemia | LILLY CO ELI (US) | 2006-11-15 | — | — | CN | disclosed |