Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27640178 | 0.98 | TSHR (0.37) | TSHRP2RX4BCHEALDH1A1HPGD | |
| SCHEMBL27655284 | 0.83 | — | — | |
| SCHEMBL27655311 | 0.79 | MAPT (0.40) | — | |
| SCHEMBL27655219 | 0.77 | CTSK (0.30) | — | |
| SCHEMBL27675096 | 0.77 | — | — | |
| SCHEMBL27660977 | 0.74 | P2RX4 (0.31) | P2RX4BCHECA12CA1CA2 | |
| SCHEMBL3830145 | 0.72 | ALDH1A1 (0.32) | TSHRP2RX4BCHEALDH1A1HPGD | |
| SCHEMBL3830139 | 0.72 | ALDH1A1 (0.32) | TSHRP2RX4BCHEALDH1A1HPGD | |
| SCHEMBL27571019 | 0.71 | P2RX4 (0.37) | TSHRP2RX4BCHEALDH1A1HPGD | |
| SCHEMBL6034344 | 0.70 | ALDH1A1 (0.33) | TSHRP2RX4BCHEALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972932-A | Compounds and methods for treating dyslipidemia | LILLY CO ELI (US) | 2007-05-30 | — | — | CN | claimed |
| CN-1863778-A | Compounds and methods for treating dyslipidemia | LILLY CO ELI (US) | 2006-11-15 | — | — | CN | claimed |
| CN-1972932-A | Compounds and methods for treating dyslipidemia | LILLY CO ELI (US) | 2007-05-30 | — | — | CN | disclosed |
| CN-1863778-A | Compounds and methods for treating dyslipidemia | LILLY CO ELI (US) | 2006-11-15 | — | — | CN | disclosed |
| EP-1670768-A1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | ELI LILLY AND COMPANY (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005037796-A1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | ELI LILLY AND COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |