Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27662576 | 0.84 | KDM4E (0.38) | KDM4EMAPK1CASP1CASP7ATM | |
| SCHEMBL4778122 | 0.83 | KDM4E (0.37) | KDM4EMAPK1CASP1CASP7ATM | |
| SCHEMBL4779619 | 0.82 | MAPT (0.45) | KDM4EMAPK1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL27662539 | 0.80 | KDM4E (0.38) | KDM4EMAPK1CASP1CASP7ATM | |
| SCHEMBL27682223 | 0.80 | MAPT (0.38) | KDM4EMAPK1CASP1CASP7ATM | |
| SCHEMBL27662582 | 0.80 | MAT2A (0.38) | SIGMAR1ADORA3ADORA1ADORA2APDGFRB | |
| SCHEMBL4769606 | 0.79 | HPGD (0.34) | KDM4EMAPK1CASP1CASP7ATM | |
| SCHEMBL4769613 | 0.79 | HPGD (0.34) | KDM4EMAPK1CASP1CASP7ATM | |
| SCHEMBL27682168 | 0.79 | TBXAS1 (0.42) | KDM4EMAPK1CASP1CASP7ATM | |
| SCHEMBL27682164 | 0.79 | ADORA2A (0.41) | KDM4EMAPK1CASP1CASP7ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980927-A | Pyrazolopyridine derivatives | ASTELLAS PHARMA INC (JP) | 2007-06-13 | — | — | CN | disclosed |