Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27842045 | 0.71 | TNKS (0.48) | KDM4EALDH1A1HPGDNQO2TNKS | |
| SCHEMBL24008917 | 0.71 | KDM4E (0.55) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11336612 | 0.69 | ABL1 (0.42) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1317916 | 0.68 | HSP90AA1 (0.47) | KDM4EALDH1A1HPGDNQO2TNKS | |
| SCHEMBL4619294 | 0.68 | AR (0.30) | — | |
| SCHEMBL30109993 | 0.68 | HSP90AA1 (0.47) | KDM4EALDH1A1HPGDNQO2TNKS | |
| SCHEMBL30013215 | 0.68 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1353177 | 0.68 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL25346041 | 0.67 | FYN (0.40) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7748193 | 0.67 | KDM4E (0.54) | KDM4EMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101024671-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2007-08-29 | — | — | CN | disclosed |
| CN-1974596-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2007-06-06 | — | — | CN | disclosed |