SCHEMBL27664201

SCHEMBL27664201

Ic1cccc(-c2ccccc2)c1.c1cc2cc-2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
ALDH1A1 P00352 1/20 0.47
KMO O15229 1/20 0.46
MEN1 O00255 1/20 0.44
ESR1 P03372 1/20 0.44
KMT2A Q03164 1/20 0.44
METAP2 P50579 1/20 0.44
MGLL Q99685 2/20 0.43
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
ALOX5 P09917 1/20 0.41
ACMSD Q8TDX5 1/20 0.41
GP6 Q9HCN6 1/20 0.41
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
NISCH Q9Y2I1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22184073 1.00 MAOA (0.48) MAOAALDH1A1KMOMEN1ESR1
SCHEMBL9959405 1.00 MAOA (0.48) MAOAALDH1A1KMOMEN1ESR1
SCHEMBL22173195 0.97 MEN1 (0.48) MAOAALDH1A1KMOMEN1ESR1
SCHEMBL17726092 0.97 MEN1 (0.48) MAOAALDH1A1KMOMEN1ESR1
SCHEMBL22167041 0.97 MEN1 (0.48) MAOAALDH1A1KMOMEN1ESR1
SCHEMBL19020250 0.97 MAOA (0.46) MAOAALDH1A1KMOMEN1ESR1
SCHEMBL1921307 0.97 ALDH1A1 (0.50) MAOAALDH1A1KMOMEN1ESR1
SCHEMBL29441211 0.97 ALDH1A1 (0.50) MAOAALDH1A1KMOMEN1ESR1
SCHEMBL23606172 0.95 MAOA (0.44) MAOAALDH1A1KMOMEN1ESR1
SCHEMBL19658882 0.95 MAOA (0.48) MAOAALDH1A1KMOMEN1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1984874-B Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO 2012-09-26 CN disclosed
CN-102643203-A Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO 2012-08-22 CN disclosed
CN-102633656-A Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO 2012-08-15 CN disclosed
CN-101094828-A Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2007-12-26 CN disclosed
CN-1984874-A Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2007-06-20 CN disclosed