Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | NCF1 | P14598 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090834 | 0.88 | ADRB2 (0.49) | ADRB2NCF1HTR6MGLL | |
| SCHEMBL2090832 | 0.88 | ADRB2 (0.49) | ADRB2NCF1HTR6DRD2MGLL | |
| SCHEMBL28761513 | 0.79 | CHRM4 (0.49) | ADRB2NCF1F10SLC6A2SLC6A4 | |
| SCHEMBL27644867 | 0.75 | ADRB2 (0.46) | ADRB2NCF1DRD2F10KCNH2 | |
| SCHEMBL27645178 | 0.75 | ADRB2 (0.51) | ADRB2NCF1DRD2F10KCNH2 | |
| SCHEMBL7136526 | 0.74 | ADRB2 (0.65) | ADRB2NCF1DRD2HRH3KDM4E | |
| SCHEMBL29722401 | 0.74 | ADRB2 (0.58) | ADRB2NCF1DRD2KDM4EF10 | |
| SCHEMBL18980471 | 0.74 | ADRB2 (0.58) | ADRB2NCF1DRD2KDM4EF10 | |
| SCHEMBL6186822 | 0.74 | ADRB2 (0.62) | ADRB2NCF1DRD2F10KCNH2 | |
| SCHEMBL27645199 | 0.74 | HRH3 (0.41) | HTR6HTR1ADRD2HTR2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |