Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666219 | 0.92 | HTR1A (0.38) | HRH3KCNN4HTR6MAOBHTR1A | |
| SCHEMBL2096558 | 0.84 | KCNN4 (0.41) | HRH3KCNN4HTR6MAOBMGLL | |
| SCHEMBL2096561 | 0.84 | MGLL (0.41) | HRH3KCNN4HTR6MAOBMGLL | |
| SCHEMBL27665953 | 0.83 | KDM4E (0.52) | KCNN4HTR6HTR1ADRD2HTR2A | |
| SCHEMBL27665965 | 0.80 | HTR1A (0.40) | HTR1ADRD2HTR2A | |
| SCHEMBL27645196 | 0.80 | DRD2 (0.41) | HTR1ADRD2HTR2ASLC6A2SLC6A4 | |
| SCHEMBL27644493 | 0.79 | TP53 (0.46) | HTR1ADRD2HTR2ASLC6A2SLC6A4 | |
| SCHEMBL2098701 | 0.77 | MGLL (0.35) | HRH3MGLLKDM4E | |
| SCHEMBL2098699 | 0.77 | HRH3 (0.34) | HRH3KCNN4MGLL | |
| SCHEMBL27645101 | 0.76 | DCPS (0.41) | HTR1ADRD2HTR2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |