Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | NCF1 | P14598 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094840 | 0.82 | CHRM4 (0.40) | CHRM4KCNH2ALDH1A1SCD | |
| SCHEMBL2094844 | 0.82 | CHRM4 (0.40) | CHRM4KCNH2ALDH1A1KDM4ESCD | |
| SCHEMBL28761513 | 0.78 | CHRM4 (0.49) | CHRM4ADRB2NCF1CNR2F10 | |
| SCHEMBL27666187 | 0.78 | CHRM4 (0.48) | CHRM4ADRB2NCF1NPC1PKM | |
| SCHEMBL27666154 | 0.74 | KCNH2 (0.54) | ADRB2NCF1KCNH2ALDH1A1KDM4E | |
| SCHEMBL27644535 | 0.74 | ADRB2 (0.51) | ADRB2NCF1CNR2PKMALOX15 | |
| SCHEMBL4018098 | 0.73 | NCF1 (0.63) | ADRB2NCF1CNR2F10PKM | |
| SCHEMBL22755427 | 0.73 | ADRB2 (0.63) | ADRB2NCF1CNR2PKMKCNH2 | |
| SCHEMBL28251236 | 0.73 | NCF1 (0.63) | ADRB2NCF1CNR2F10PKM | |
| SCHEMBL21001109 | 0.72 | ADRB2 (0.52) | CHRM4ADRB2NCF1CNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |