Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | NCF1 | P14598 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | GPR6 | P46095 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401253 | 0.81 | KCNH2 (0.64) | SIGMAR1NCF1KCNH2MAPTDRD4 | |
| SCHEMBL27470939 | 0.78 | CYP3A4 (0.57) | NCF1DRD3CYP3A4CHRM1OPRK1 | |
| SCHEMBL27470403 | 0.78 | CYP3A4 (0.71) | NCF1DRD3CYP3A4CHRM1OPRK1 | |
| SCHEMBL27666154 | 0.77 | KCNH2 (0.54) | NCF1DRD3CYP3A4CHRM1OPRK1 | |
| SCHEMBL13987031 | 0.77 | NR4A1 (0.55) | NCF1DRD3KCNH2MAPTDRD2 | |
| SCHEMBL13987033 | 0.74 | KCNH2 (0.61) | HTR6DRD3CYP3A4KCNH2HRH3 | |
| SCHEMBL8130723 | 0.74 | SIGMAR1 (0.58) | SIGMAR1HTR6MAPTTSHRDRD4 | |
| SCHEMBL2165351 | 0.74 | DHFR (0.62) | SIGMAR1NCF1DRD3MAPTTSHR | |
| SCHEMBL8173934 | 0.74 | SIGMAR1 (0.70) | SIGMAR1DRD3MAPTTSHRDRD2 | |
| SCHEMBL9229789 | 0.73 | KCNH2 (0.60) | DRD3CYP3A4CHRM1OPRK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |