Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PLG | P00747 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | CCR3 | P51677 | 6/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20191355 | 0.84 | POLB (0.50) | GBA1POLBPLGSLC6A4CCR3 | |
| SCHEMBL16138429 | 0.82 | GBA1 (0.59) | GBA1POLBPLGSLC6A4CCR3 | |
| SCHEMBL7972742 | 0.82 | POLB (0.48) | GBA1POLBPLGSLC6A4CCR3 | |
| Hydrochloric Acid SCHEMBL3096697 | 0.81 | GBA1 (0.50) | GBA1POLBPLGSLC6A4CCR3 | |
| SCHEMBL23775740 | 0.81 | POLB (0.57) | GBA1POLBPLG | |
| SCHEMBL5919208 | 0.81 | GBA1 (0.58) | GBA1POLBPLGCCR3 | |
| SCHEMBL9112753 | 0.81 | POLB (0.57) | GBA1POLBPLG | |
| SCHEMBL23775758 | 0.81 | POLB (0.57) | GBA1POLBPLG | |
| SCHEMBL7864876 | 0.81 | POLB (0.57) | GBA1POLBPLG | |
| SCHEMBL7864879 | 0.81 | POLB (0.57) | GBA1POLBPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |