Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PLG | P00747 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23775758 | 1.00 | POLB (0.57) | POLBPLGGBA1MEN1KMT2A | |
| SCHEMBL9885538 | 1.00 | POLB (0.57) | POLBPLGGBA1MEN1KMT2A | |
| SCHEMBL5692520 | 0.90 | POLB (0.63) | POLBPLGGBA1 | |
| SCHEMBL7460081 | 0.83 | LTA4H (0.40) | POLBPLG | |
| SCHEMBL7460084 | 0.83 | LTA4H (0.40) | POLBPLG | |
| SCHEMBL5486005 | 0.82 | POLB (0.47) | POLBPLGMEN1KMT2A | |
| SCHEMBL27647450 | 0.82 | POLB (0.47) | POLBPLGMEN1KMT2A | |
| SCHEMBL27666282 | 0.81 | GBA1 (0.59) | POLBPLGGBA1 | |
| SCHEMBL7864876 | 0.79 | POLB (0.57) | POLBPLGGBA1MEN1KMT2A | |
| SCHEMBL7864879 | 0.79 | POLB (0.57) | POLBPLGGBA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236122-B2 | Triterpene amine derivatives | DFH THERAPEUTICS (US) | 2022-02-01 | — | — | US | disclosed |
| US-20210253627-A1 | TRITERPENE AMINE DERIVATIVES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253627-A1 | TRITERPENE AMINE DERIVATIVES | BET1, PGGT1B, NFATC1 | POLB 1502/4885PLG 4717/4885GBA1 902/4885 |
| US-11236122-B2 | Triterpene amine derivatives | BET1, PGGT1B, NFATC1 | POLB 1502/4885PLG 4717/4885GBA1 902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.