Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 11/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203359 | 0.88 | NR3C1 (0.46) | NR3C1NR3C2 | |
| SCHEMBL1634784 | 0.85 | NR3C2 (0.53) | NR3C1NR3C2 | |
| SCHEMBL6639450 | 0.80 | HTR2C (0.43) | NR3C1NR3C2 | |
| SCHEMBL13823431 | 0.79 | NR3C2 (0.50) | NR3C1NR3C2 | |
| SCHEMBL27813424 | 0.78 | DDR1 (0.37) | — | |
| SCHEMBL27686485 | 0.78 | RIPK1 (0.34) | NR3C1NR3C2PGR | |
| SCHEMBL4490249 | 0.77 | NR3C2 (0.51) | NR3C1NR3C2 | |
| SCHEMBL3889197 | 0.76 | NR3C2 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL1492607 | 0.76 | NR3C2 (0.53) | NR3C1NR3C2 | |
| SCHEMBL10313421 | 0.76 | NR3C2 (0.50) | NR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1976705-B | 1,1, 1-trifluoro-4-phenyl-4-methyl-2- (1H-pyrrolo [2,3-C ] pyridin-2-ylmethyl) pentan-2-ol derivatives and related compounds as glucocorticoid ligands for the treatment of inflammatory diseases and diabetes | BOEHRINGER INGELHEIM PHARMA | 2010-09-22 | — | — | CN | disclosed |
| CN-1976705-A | 1,1, 1-trifluoro-4-phenyl-4-methyl-2- (1H-pyrrolo [2, 3-C ] pyridin-2-ylmethyl) pentan-2-ol derivatives and related compounds as glucocorticoid ligands for the treatment of inflammatory diseases and diabetes | BOEHRINGER INGELHEIM PHARMA (US) | 2007-06-06 | — | — | CN | disclosed |