Sugi Predict

Sugi Predict / Compounds / SCHEMBL276676

SCHEMBL276676

SCHEMBL276676

O=CCCC(=O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR4A2 P43354 1/20 0.65
▸ TDP1 Q9NUW8 3/20 0.59
▸ MAPT P10636 3/20 0.59
▸ LMNA P02545 3/20 0.59
▸ L3MBTL1 Q9Y468 2/20 0.59
▸ ALDH1A1 P00352 3/20 0.59
▸ GAA P10253 1/20 0.59
▸ CYP2C19 P33261 1/20 0.59
▸ MAPK1 P28482 3/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ CYP3A4 P08684 1/20 0.54
▸ HPGD P15428 1/20 0.54
▸ ALOX15 P16050 1/20 0.54
▸ CES1 P23141 1/20 0.54
▸ HDAC1 Q13547 5/20 0.53
▸ HDAC8 Q9BY41 5/20 0.53
▸ HDAC3 O15379 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3378823 0.88 SMN1; SMN2 (0.70) NR4A2MAPTLMNAL3MBTL1ALDH1A1
SCHEMBL946292 0.88 TDP1 (0.67) NR4A2TDP1MAPTLMNAL3MBTL1
SCHEMBL7546343 0.86 TDP1 (0.70) NR4A2TDP1MAPTLMNAL3MBTL1
SCHEMBL7551879 0.84 TDP1 (0.74) NR4A2TDP1MAPTLMNAL3MBTL1
SCHEMBL28052282 0.84 TDP1 (0.74) NR4A2TDP1MAPTLMNAL3MBTL1
SCHEMBL19043378 0.84 MMP1 (0.60) NR4A2TDP1MAPTLMNAL3MBTL1
SCHEMBL30121738 0.81 NR4A2 (0.85) NR4A2TDP1MAPTLMNAL3MBTL1
SCHEMBL719034 0.81 NR4A2 (0.85) NR4A2TDP1MAPTLMNAL3MBTL1
SCHEMBL317112 0.81 MAPT (0.57) NR4A2TDP1MAPTLMNAL3MBTL1
SCHEMBL8608674 0.81 TDP1 (0.57) NR4A2TDP1MAPTLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561885-A Mechanochromism multifunctional organic compound and preparation method and application thereof 北京大学 2024-08-30 — — CN claimed
CN-115968242-A 2D/3D perovskite thin film with transfer printing assistance for in-situ growth, and preparation method and application thereof 吉林大学 2023-04-14 — — CN claimed
CN-108314599-A A kind of method that aldehyde or alcohol are directly translated into carboxylic acid 中国科学技术大学 2018-07-24 — — CN claimed
US-20090300800-A1 D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation BASF PLANT SCIENCE GMBH (DE) 2009-12-03 — — US claimed
US-20070248996-A1 Modulators of beta-amyloid peptide aggregation comprising D-amino acids PARAECIS PHARMACEUTICALS, INC. (US) 2007-10-25 — — US claimed
US-20060014696-A1 Modulators of beta-amyloid peptide aggregation comprising D-amino acids PRAECIS PHARMACEUTICALS, INC. (US) 2006-01-19 — — US claimed
EP-0929574-B1 MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS PRAECIS PHARM INC (US) 2005-06-29 — — EP claimed
EP-1126833-A4 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES INC (US) 2004-09-08 — — EP claimed
EP-1332150-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF Chattopadhyaya, Jyoti (SE) 2003-08-06 — — EP claimed
US-20020103134-A1 Modulators of beta-amyloid peptide aggregation comprising D-amino acids PRAECIS PHARMACEUTICALS INC. 2002-08-01 — — US claimed
WO-1998034111-A1 TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-08-06 — — WO claimed
WO-1998034115-A1 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-08-06 — — WO claimed
WO-1998008868-A9 MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS — 1998-05-28 — — WO claimed
WO-1998008868-A1 MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS PRAECIS PHARMACEUTICALS INCORPORATED (US) 1998-03-05 — — WO claimed
WO-1997041139-A2 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KOESTER HUBERT (US) 1997-11-06 — — WO claimed
EP-0766966-A2 Method of treating insulin resistance ELI LILLY AND COMPANY (US) 1997-04-09 — — EP claimed
WO-1997009060-A1 METHOD OF TREATING INSULIN RESISTANCE ELI LILLY AND COMPANY (US) 1997-03-13 — — WO claimed
EP-0648220-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA, Jyoti (SE) 1995-04-19 — — EP claimed
WO-1994010128-A1 NOVEL PHOTOREACTIVE PROTECTING GROUPS AFFYMAX TECHNOLOGIES N.V. (AN) 1994-05-11 — — WO claimed
US-5279818-A Permanent waving with silicones DOW CORNING CORPORATION (US) 1994-01-18 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070248996-A1 Modulators of beta-amyloid peptide aggregation comprising D-amino acids APP, IAPP, BACE1 NR4A2 2872/4885TDP1 1980/4885MAPT 121/4885
US-20020103134-A1 Modulators of beta-amyloid peptide aggregation comprising D-amino acids IAPP, APP, VIP NR4A2 3070/4885TDP1 1944/4885MAPT 297/4885
US-20060014696-A1 Modulators of beta-amyloid peptide aggregation comprising D-amino acids APP, IAPP, BACE1 NR4A2 2872/4885TDP1 1980/4885MAPT 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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