Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546343 | 0.94 | TDP1 (0.70) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL7551879 | 0.92 | TDP1 (0.74) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL28052282 | 0.92 | TDP1 (0.74) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL276676 | 0.88 | NR4A2 (0.65) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL19043214 | 0.85 | MMP1 (0.57) | TDP1MAPTLMNAL3MBTL1RAB9A | |
| SCHEMBL19043116 | 0.83 | HDAC8 (0.63) | TDP1MAPTLMNAL3MBTL1HDAC1 | |
| SCHEMBL7068671 | 0.83 | TDP1 (0.95) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL1052631 | 0.83 | TDP1 (0.86) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL5181691 | 0.82 | NPC1 (0.70) | TDP1MAPTLMNAL3MBTL1RAB9A | |
| SCHEMBL2745649 | 0.82 | TDP1 (0.64) | TDP1MAPTLMNAL3MBTL1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061645-B | The preparation method of highly viscous Pioloform, polyvinyl acetal | 湖州鑫富新材料有限公司 | 2017-08-25 | — | — | CN | claimed |
| US-20120329711-A1 | GLP-1 RECEPTOR AGONIST COMPOUNDS WITH A MODIFIED N-TERMINUS | NORDISK A/S (DK) | 2012-12-27 | — | — | US | claimed |
| EP-1210321-A1 | AMINOSALICYLCLIC ACID AMIDES AND THEIR USE FOR COMBATING ORGANISMS THAT ARE HARMFUL TO PLANTS | Bayer Aktiengesellschaft (DE) | 2002-06-05 | — | — | EP | claimed |
| WO-2001012587-A1 | AMINOSALICYLCLIC ACID AMIDES AND THEIR USE FOR COMBATING ORGANISMS THAT ARE HARMFUL TO PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | claimed |
| US-20220401430-A1 | ALLOSTERIC MODULATORS OF THE MU OPIOID RECEPTOR | Chiromics, LLC | 2022-12-22 | — | — | US | disclosed |
| US-11071731-B2 | Allosteric modulators of the mu opioid receptor | Chiromics, LLC (US) | 2021-07-27 | — | — | US | disclosed |
| US-20200276177-A1 | Allosteric Modulators of the Mu Opioid Receptor | Chiromics, LLC (US) | 2020-09-03 | — | — | US | disclosed |
| US-10603313-B2 | Allosteric modulators of the mu opioid receptor | Chiromics, LLC (US) | 2020-03-31 | — | — | US | disclosed |
| US-20190030020-A1 | Allosteric Modulators of the Mu Opioid Receptor | Chiromics, LLC (US) | 2019-01-31 | — | — | US | disclosed |
| CN-108566947-A | A kind of foam disinfectant auxiliary agent, preparation method and foamaseptic prepared therefrom | 洛阳惠中兽药有限公司 | 2018-09-25 | — | — | CN | disclosed |
| EP-3368091-A1 | BIFUNCTIONAL PRODRUGS | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts (DE) | 2018-09-05 | — | — | EP | disclosed |
| US-20180093981-A1 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors | GENZYME CORPORATION | 2018-04-05 | — | — | US | disclosed |
| EP-1740574-A2 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | Otsuka Pharmaceutical Company, Limited (JP) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105778-A2 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-11-10 | — | — | WO | disclosed |
| EP-1210321-A1 | AMINOSALICYLCLIC ACID AMIDES AND THEIR USE FOR COMBATING ORGANISMS THAT ARE HARMFUL TO PLANTS | Bayer Aktiengesellschaft (DE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012587-A1 | AMINOSALICYLCLIC ACID AMIDES AND THEIR USE FOR COMBATING ORGANISMS THAT ARE HARMFUL TO PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |
| US-4978530-A | Sanitized, disinfected and sporicidal articles, and processes for sanitizing, disinfecting and rendering objects sporicidal | HEALTH CARE PRODUCTS, INC. (CA) | 1990-12-18 | — | — | US | disclosed |
| US-4259236-A | COLORFAST RED SHADES ON POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| US-4101541-A | DYES FOR POLYESTERS OR POLYPROPYLENE | CIBA-GEIGY CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-3998805-A | MONOAZO DYES; POLYESTERS; YELLOW, RED, OR ORANGE SHADES | CIBA-GEIGY CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10603313-B2 | Allosteric modulators of the mu opioid receptor | OPRM1, OPRK1, OPRD1 | TDP1 3598/4885MAPT 1331/4885LMNA 4854/4885 |
| US-20220401430-A1 | ALLOSTERIC MODULATORS OF THE MU OPIOID RECEPTOR | OPRM1, OPRK1, OPRD1 | TDP1 3598/4885MAPT 1331/4885LMNA 4854/4885 |
| US-20200276177-A1 | Allosteric Modulators of the Mu Opioid Receptor | OPRM1, OPRK1, OPRD1 | TDP1 3598/4885MAPT 1331/4885LMNA 4854/4885 |
| US-20190030020-A1 | Allosteric Modulators of the Mu Opioid Receptor | OPRM1, OPRK1, OPRD1 | TDP1 4457/4885MAPT 2178/4885LMNA 4862/4885 |
| US-20180093981-A1 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors | ASAH2, GBA1, GAA | TDP1 2809/4885MAPT 2401/4885LMNA 1311/4885 |
| US-20120329711-A1 | GLP-1 RECEPTOR AGONIST COMPOUNDS WITH A MODIFIED N-TERMINUS | GLP1R, GIPR, GCGR | TDP1 4293/4885MAPT 3924/4885LMNA 3328/4885 |
| US-11071731-B2 | Allosteric modulators of the mu opioid receptor | OPRM1, OPRK1, OPRD1 | TDP1 3598/4885MAPT 1331/4885LMNA 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.