Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.48 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.47 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.47 |
| ▸ | VNN1 | O95497 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | KLK1 | P06870 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647891 | 0.87 | F2 (0.46) | AURKARPS6KB1MEN1KMT2APPIA | |
| SCHEMBL27647928 | 0.85 | AURKA (0.50) | AURKARPS6KB1ZAP70KARS1NPC1 | |
| SCHEMBL27647949 | 0.76 | PPIA (0.46) | NPC1KMT2APPIA | |
| SCHEMBL27647929 | 0.76 | AURKA (0.53) | AURKARPS6KB1PPARANPC1KDM4E | |
| SCHEMBL27668372 | 0.76 | F2 (0.48) | ZAP70KARS1NPC1KDM4EASPH | |
| SCHEMBL16991862 | 0.75 | KDM4E (0.56) | AURKARPS6KB1VNN1PPARANPC1 | |
| SCHEMBL1715544 | 0.74 | MEN1 (0.60) | AURKARPS6KB1VNN1NPC1KDM4E | |
| SCHEMBL1714982 | 0.74 | MEN1 (0.60) | AURKARPS6KB1VNN1NPC1KDM4E | |
| SCHEMBL26922126 | 0.74 | KDM4E (0.55) | AURKARPS6KB1ZAP70KARS1VNN1 | |
| SCHEMBL21384718 | 0.73 | NPC1 (0.57) | AURKARPS6KB1ZAP70KARS1VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1906155-A | Novel hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA AS (DK) | 2007-01-31 | — | — | CN | claimed |
| CN-1906155-A | Novel hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA AS (DK) | 2007-01-31 | — | — | CN | disclosed |