Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.48 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27668348 | 0.85 | AURKA (0.48) | AURKARPS6KB1ZAP70KARS1KMT2A | |
| SCHEMBL27647891 | 0.82 | F2 (0.46) | AURKARPS6KB1KMT2AMEN1ALDH1A1 | |
| SCHEMBL27647949 | 0.81 | PPIA (0.46) | KMT2AALDH1A1TP53NPC1RAB9A | |
| SCHEMBL4599397 | 0.76 | RXRA (0.60) | KDM4EALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL27668372 | 0.76 | F2 (0.48) | ZAP70KARS1KMT2AMEN1KDM4E | |
| SCHEMBL1716082 | 0.76 | NPC1 (0.57) | AURKARPS6KB1KMT2AMEN1PLA2G1B | |
| SCHEMBL1376602 | 0.72 | KDM4E (0.59) | AURKARPS6KB1KMT2AMEN1KDM4E | |
| SCHEMBL5743109 | 0.72 | FOLH1 (0.57) | MAPTL3MBTL1TDP1RXRAHTT | |
| SCHEMBL5988969 | 0.69 | FOLH1 (0.50) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL1373630 | 0.69 | CYP1A2 (0.56) | AURKARPS6KB1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1906155-A | Novel hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA AS (DK) | 2007-01-31 | — | — | CN | claimed |
| CN-1906155-A | Novel hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA AS (DK) | 2007-01-31 | — | — | CN | disclosed |