Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647891 | 0.89 | F2 (0.46) | F2SMN1; SMN2ALDH1A1ABCB1PPIA | |
| SCHEMBL27647928 | 0.76 | AURKA (0.50) | KDM4ESMN1; SMN2ALDH1A1HPGDPPIA | |
| SCHEMBL27668348 | 0.76 | AURKA (0.48) | KDM4EPPIAMAPTMEN1KMT2A | |
| SCHEMBL15529333 | 0.75 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL27647949 | 0.74 | PPIA (0.46) | SMN1; SMN2ALDH1A1PPIAKMT2ARAB9A | |
| SCHEMBL1715666 | 0.73 | MAPT (0.63) | F2KCNH2GRIN2BKDM4EALDH1A1 | |
| SCHEMBL15529130 | 0.72 | KDM4E (0.48) | F2KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL27865830 | 0.71 | PPIA (0.44) | KDM4EALDH1A1PPIAMAPTHTT | |
| SCHEMBL3716881 | 0.71 | MAPT (0.70) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL5743109 | 0.70 | FOLH1 (0.57) | MAPTHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1906155-A | Novel hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA AS (DK) | 2007-01-31 | — | — | CN | claimed |
| CN-1906155-A | Novel hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA AS (DK) | 2007-01-31 | — | — | CN | disclosed |