Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 13/20 | 0.50 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28761811 | 0.91 | PTGER4 (0.55) | PTGER4 | |
| SCHEMBL4480347 | 0.73 | F2RL3 (0.67) | PTGER4F2RL3ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4470865 | 0.71 | PTGER4 (0.64) | PTGER4 | |
| SCHEMBL1170095 | 0.70 | SCN8A (0.50) | PTGER4ALDH1A1 | |
| SCHEMBL1170105 | 0.70 | CYP1A2 (0.50) | PTGER4ALDH1A1 | |
| SCHEMBL25247023 | 0.68 | SCN8A (0.49) | PTGER4ALDH1A1LMNA | |
| SCHEMBL18096451 | 0.68 | PTGER4 (0.47) | PTGER4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11616869 | 0.68 | POLB (0.48) | F2RL3ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL12913015 | 0.68 | KMT2A (0.41) | PTGER4ALDH1A1 | |
| SCHEMBL4487658 | 0.68 | HDAC6 (0.56) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100516049-C | Antiangiogenic agent N2Synthesis of- (substituted arylmethyl) -3- (substituted phenyl) indazoles | YUNG SHIN PHARM IND CO LTD (CN) | 2009-07-22 | — | — | CN | disclosed |
| CN-1962640-A | Novel anti-angiogenic drug N2Synthesis of- (substituted arylmethyl) -3- (substituted phenyl) indazoles | YUNG SHIN PHARM IND CO LTD (CN) | 2007-05-16 | — | — | CN | disclosed |