Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697595 | 0.67 | KMT2A (0.60) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL6885150 | 0.66 | KMT2A (0.50) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL166548 | 0.66 | CYP3A4 (0.53) | KMT2AHSD17B10ALDH1A1HCAR2MAPK1 | |
| SCHEMBL14348812 | 0.65 | KMT2A (0.46) | KMT2AMEN1HTTGFERHSD17B10 | |
| Formaldehyde SCHEMBL28517301 | 0.65 | CYP3A4 (0.51) | KMT2AHSD17B10ALDH1A1HCAR2MAPK1 | |
| SCHEMBL3635540 | 0.65 | MAPT (0.39) | KMT2AMEN1HSD17B10ATMALDH1A1 | |
| SCHEMBL37382 | 0.65 | ALDH1A1 (0.68) | KMT2AALDH1A1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL9654656 | 0.65 | ALDH1A1 (0.50) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL5793033 | 0.65 | ALDH1A1 (0.53) | KMT2AALDH1A1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL22162939 | 0.65 | KMT2A (0.54) | KMT2AMEN1HTTGFERHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776345-B1 | Method of preparing N2-functionalised indazolinone derivatives | UNIV ST ANDREWS (GB) | 2013-02-13 | — | — | EP | disclosed |
| US-7868184-B2 | Multicore indazolinone library | The University of the University of St. Andrews (GB) | 2011-01-11 | — | — | US | disclosed |
| US-7868184-B2 | Multicore indazolinone library | The University of the University of St. Andrews (GB) | 2011-01-11 | — | — | US | disclosed |
| US-20070179294-A1 | Multicore indazolinone library | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2007-08-02 | — | — | US | disclosed |
| US-20070179294-A1 | Multicore indazolinone library | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179294-A1 | Multicore indazolinone library | IPMK, TTK, IWS1 | KMT2A 1621/4885MEN1 145/4885HTT 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.