Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306517 | 0.82 | TSHR (0.35) | P2RX7YTHDC1 | |
| SCHEMBL28786819 | 0.80 | TDP1 (0.41) | TDP1TAAR1 | |
| SCHEMBL32679671 | 0.78 | TDP1 (0.39) | TDP1TAAR1 | |
| SCHEMBL27953771 | 0.78 | TDP1 (0.39) | TDP1TAAR1 | |
| SCHEMBL30600 | 0.75 | TDP1 (0.55) | TDP1TAAR1 | |
| SCHEMBL8089687 | 0.75 | CYSLTR2 (0.45) | — | |
| SCHEMBL11688468 | 0.75 | TDP1 (0.37) | TDP1 | |
| SCHEMBL6299275 | 0.75 | P2RX7 (0.35) | P2RX7TAAR1YTHDC1 | |
| SCHEMBL22864695 | 0.74 | TAAR1 (0.58) | TAAR1YTHDC1 | |
| SCHEMBL3518623 | 0.73 | ALDH1A1 (0.38) | P2RX7YTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218565-A | Spiral shell oxindole compounds and the purposes as therapeutical agent thereof | XENON PHARMACEUTICALS INC | 2016-01-06 | — | — | CN | disclosed |
| CN-105175433-A | Spiro-oxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC | 2015-12-23 | — | — | CN | disclosed |
| CN-103764648-A | Pyrrolidin-3-yl acetic acid derivatives | EISAI R&D MAN CO LTD | 2014-04-30 | — | — | CN | disclosed |
| CN-103664973-A | Spiro-oxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC | 2014-03-26 | — | — | CN | disclosed |
| CN-102256983-A | Spirooxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC | 2011-11-23 | — | — | CN | disclosed |
| CN-1902241-B | Haloaluminoxane compositions, their preparation and their use in catalysis | ALBEMARLE CORP | 2011-03-30 | — | — | CN | disclosed |
| CN-1902241-A | Haloaluminoxane compositions, their preparation and their use in catalysis | ALBEMARLE CORP (US) | 2007-01-24 | — | — | CN | disclosed |