Methacrylic Acid

Methacrylic Acid

SCHEMBL27670375

C=C(C)C(=O)O.CCCCOCCOC(C)=O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
TSHR P16473 6/20 0.52
THRB P10828 2/20 0.46
CYP3A4 P08684 1/20 0.40
CES2 O00748 1/20 0.39
HPGD P15428 1/20 0.39
RARB P10826 1/20 0.39
ATM Q13315 1/20 0.37
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
DGKA P23743 1/20 0.36
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTGS2 P35354 1/20 0.35
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL2150763 0.89 ALDH1A1 (0.68) ALDH1A1TSHRTHRBCYP3A4CES2
Acetic Acid SCHEMBL22394365 0.89 ALDH1A1 (0.68) ALDH1A1TSHRTHRBCYP3A4CES2
Acetic Acid SCHEMBL20340243 0.89 ALDH1A1 (0.68) ALDH1A1TSHRTHRBCYP3A4CES2
Acetic Acid Butyl Ester SCHEMBL4017586 0.89 ALDH1A1 (0.75) ALDH1A1TSHRTHRBHPGDATM
Methacrylic Acid SCHEMBL1123959 0.89 TSHR (0.50) ALDH1A1TSHRTHRBCYP3A4CES2
SCHEMBL22372 0.89 ALDH1A1 (0.74) ALDH1A1TSHRTHRBCYP3A4CES2
SCHEMBL2702326 0.89 ALDH1A1 (0.74) ALDH1A1TSHRTHRBCYP3A4CES2
SCHEMBL13523596 0.89 ALDH1A1 (0.74) ALDH1A1TSHRTHRBCYP3A4CES2
SCHEMBL48354 0.89 ALDH1A1 (0.74) ALDH1A1TSHRTHRBCYP3A4CES2
SCHEMBL8125550 0.89 ALDH1A1 (0.74) ALDH1A1TSHRTHRBCYP3A4CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103254974-B There is the lubricating oil composition of good frictional properties EVONIK ROHMAX ADDITIVES GMBH (DE) 2015-11-11 CN disclosed
CN-101845284-B Pressure-sensitive adhesives for bonding printing plates TESA SE 2014-04-02 CN disclosed
CN-101633821-B Flexible heated area element TESA SE 2013-09-11 CN disclosed
CN-103254974-A Lubricating oil composition with good frictional properties ROHMAX ADDITIVES GMBH 2013-08-21 CN disclosed
CN-101845284-A The pressure sensitive adhesive that is used for bonding printing plates TESA SE 2010-09-29 CN disclosed
CN-101633821-A Flexible heated area element TESA SE 2010-01-27 CN disclosed
CN-101226787-A Dielectric layer forming composition, flake, substrate, method for manufacturing substrate and plasma display plate LINTEC CO LTD (JP) 2008-07-23 CN disclosed
CN-1977035-A Lubricating oil composition having excellent frictional properties ROHMAX ADDITIVES GMBH (DE) 2007-06-06 CN disclosed