SCHEMBL276704

SCHEMBL276704

O=S(=O)(O[SiH2][SiH2]OS(=O)(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
F2 P00734 2/20 0.31
PRSS1 P07477 2/20 0.31
PRSS2 P07478 2/20 0.31
PRSS3 P35030 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8897719 0.86 CA1 (0.30) CA1CA2CA7CA13
SCHEMBL3958177 0.77 CA1 (0.32) CA1CA2CA7CA13
SCHEMBL2904316 0.77 CA1 (0.38) CA1CA2CA7CA13F2
SCHEMBL2734778 0.77 CA1 (0.32) CA1CA2CA7CA13
SCHEMBL8898496 0.77
SCHEMBL8896926 0.77
SCHEMBL8895821 0.77
SCHEMBL16469194 0.73 F2 (0.30) F2PRSS1PRSS2PRSS3
SCHEMBL30655904 0.73 F2 (0.30) F2PRSS1PRSS2PRSS3
SCHEMBL538605 0.73 F2 (0.30) F2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524582-B2 Silicon-germanium hydrides and methods for making and using same THE ARIZONA BOARD OF REGENTS (US) 2013-09-03 US disclosed
US-8518360-B2 Silicon-germanium hydrides and methods for making and using same ARIZONA BOARD OF REGENTS, A CORPORATE BODY ORGANIZED UNDER ARIZONA LAW, ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY 2013-08-27 US disclosed
EP-1951617-B1 NOVEL SILICON-GERMANIUM HYDRIDES AND METHODS FOR MAKING AND USING SAME UNIV ARIZONA (US) 2013-08-21 EP disclosed
EP-1960310-B1 SILICON-GERMANIUM HYDRIDES AND METHODS FOR MAKING AND USING SAME UNIV ARIZONA (US) 2013-08-21 EP disclosed
US-20130032857-A1 Silicon-Germanium Hydrides and Methods for Making and Using Same THE ARIZONA BOARD OF REGENTS, A BODY CORPORATE ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2013-02-07 US disclosed
US-20120217618-A1 Silicon-Germanium Hydrides and Methods for Making and Using Same The Arizona Board of Regents, a body corporated acting on behalf of Arizona State University (US) 2012-08-30 US disclosed
US-8216537-B2 Silicon-germanium hydrides and methods for making and using same ARIZONA BOARD OF REGENTS (US) 2012-07-10 US disclosed
US-8133802-B2 Silicon-germanium hydrides and methods for making and using same ARIZONA BOARD OF REGENTS (US) 2012-03-13 US disclosed
US-20100012972-A1 Silicon-Germanium Hydrides and Methods for Making and Using Same The Arizona Board of Regents, a body corparate acting onbehalf of Arizona State University (US) 2010-01-21 US disclosed
US-20090050935-A1 Silicon-Germanium Hydrides and Methods for Making and Using Same THE ARIZONA BOARD OFG REGENTS, A BODY CORPORATE ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2009-02-26 US disclosed