SCHEMBL538605

SCHEMBL538605

CC(C)(C)[SiH2]OS(=O)(=O)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30655904 1.00 F2 (0.30) F2PRSS1PRSS2PRSS3
SCHEMBL3958177 0.79 CA1 (0.32)
SCHEMBL28408539 0.78
SCHEMBL3435198 0.78
SCHEMBL28408544 0.75 F2 (0.31) F2PRSS1PRSS2PRSS3
SCHEMBL22325671 0.74
SCHEMBL28890290 0.74
SCHEMBL2904316 0.74 CA1 (0.38) F2PRSS1PRSS2PRSS3
SCHEMBL28639467 0.74
SCHEMBL276704 0.73 CA1 (0.35) F2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428175-B1 METHOD FOR PRODUCING OLIGOSACCHARIDES AND POLYSACCHARIDES HAVING NON-PROTECTED SULFATE GROUPS GLYTECH INC (JP) 2024-09-25 EP claimed
US-10797348-B2 Electrolyte and lithium-ion battery CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2020-10-06 US claimed
CN-108258297-B Electrolyte and lithium ion battery 宁德时代新能源科技股份有限公司 2020-07-17 CN claimed
CN-110878110-A Preparation method of enol-type glycoside 复旦大学 2020-03-13 CN claimed
CN-106715448-B Process for preparing tris (trialkylsilyl) phosphine SK化学公司 2020-03-03 CN claimed
EP-3222623-B1 METHOD FOR PREPARING TRIS(TRIALKYLSILYL)PHOSPHINE SK CHEMICALS CO LTD (KR) 2019-08-28 EP claimed
US-10040809-B2 Method for preparing tris(trialkylsilyl)phosphine SK CHEMICALS CO., LTD. (KR) 2018-08-07 US claimed
US-20180191032-A1 ELECTROLYTE AND LITHIUM-ION BATTERY CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITED (CN) 2018-07-05 US claimed
EP-3222623-A1 METHOD FOR PREPARING TRIS(TRIALKYLSILYL)PHOSPHINE SK Chemicals Co., Ltd. (KR) 2017-09-27 EP claimed
US-20170226138-A1 METHOD FOR PREPARING TRIS(TRIALKYLSILYL)PHOSPHINE SK CHEMICALS CO., LTD. (KR) 2017-08-10 US claimed
EP-4741410-A1 SOLUBILIZATION GROUP FOR POORLY WATER-SOLUBLE PROTEINS Glytech, Inc. (JP) 2026-05-13 EP disclosed
US-20240391951-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE GLYTECH INC (JP) 2024-11-28 US disclosed
US-12103947-B2 Methods for producing peptide thioester and peptide GLYTECH, INC. (JP) 2024-10-01 US disclosed
EP-3428175-B1 METHOD FOR PRODUCING OLIGOSACCHARIDES AND POLYSACCHARIDES HAVING NON-PROTECTED SULFATE GROUPS GLYTECH INC (JP) 2024-09-25 EP disclosed
US-20230143844-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE GLYTECH, INC. (JP) 2023-05-11 US disclosed
CN-102378775-A Multibranched polyoxyalkylene compound and process for producing the same NOF CORP 2012-03-14 CN disclosed
EP-2415800-A1 HYPERBRANCHED POLYOXYALKYLENE COMPOUND AND METHOD FOR PRODUCING SAME NOF Corporation (JP) 2012-02-08 EP disclosed
US-20100261863-A1 MULTIBRANCHED POLYOXYALKYLENE COMPOUND AND PRODUCING METHOD THEREOF NOF CORPORATION (JP) 2010-10-14 US disclosed
US-20070219161-A1 Preparation Process Of Oligoglycosaminoglycan, And Reducing End Glucuronic Acid Type Oligochondroitin Sulfate And Pharmaceutical Composition Comprising The Same TAISHO PHARMACEUTICAL CO., LTD (JP) 2007-09-20 US disclosed
WO-2007027752-A1 CATALYTIC REACTIONS INVOLVING ALKENES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219161-A1 Preparation Process Of Oligoglycosaminoglycan, And Reducing End Glucuronic Acid Type Oligochondroitin Sulfate And Pharmaceutical Composition Comprising The Same OSTC, B3GAT3, CSGALNACT1 F2 4260/4885PRSS1 3000/4885PRSS2 3054/4885
US-20230143844-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE QPCT, PTMS, QPCTL F2 1038/4885PRSS1 1451/4885PRSS2 1164/4885
US-20170226138-A1 METHOD FOR PREPARING TRIS(TRIALKYLSILYL)PHOSPHINE INPPL1, TYMP, PHOSPHO1 F2 1607/4885PRSS1 1244/4885PRSS2 600/4885
US-10040809-B2 Method for preparing tris(trialkylsilyl)phosphine INPPL1, TYMP, PHOSPHO1 F2 1607/4885PRSS1 1244/4885PRSS2 600/4885
US-20100261863-A1 MULTIBRANCHED POLYOXYALKYLENE COMPOUND AND PRODUCING METHOD THEREOF OPRM1, AOC2, OPRK1 F2 2847/4885PRSS1 4213/4885PRSS2 4417/4885
US-12103947-B2 Methods for producing peptide thioester and peptide QPCT, QPCTL, PTMS F2 970/4885PRSS1 1474/4885PRSS2 1139/4885
US-20240391951-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE QPCT, PTMS, QPCTL F2 1038/4885PRSS1 1451/4885PRSS2 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.