Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13929453 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL12404098 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL24405179 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL13470194 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL14451342 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL2405274 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL16499642 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL5519093 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL20501772 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL15511981 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1894206-A | N-substituted N-sulfonylaminocyclopropane compounds and pharmaceutical use thereof | JAPAN TOBACCO INC (JP) | 2007-01-10 | — | — | CN | disclosed |