Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13929453 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL11051182 | 0.92 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL11051190 | 0.92 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL21494357 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL5523736 | 0.84 | L3MBTL1 (0.59) | ALDH1A1NPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5523733 | 0.84 | L3MBTL1 (0.59) | ALDH1A1NPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16499644 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL16499815 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL16499642 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| Benzyl Alcohol SCHEMBL27670531 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985755-B2 | 2,4-diaminoquinazolines for spinal muscular atrophy | FAMILIES OF SPINAL MUSCULAR ATROPHY (US) | 2011-07-26 | — | — | US | disclosed |