SCHEMBL2767111

SCHEMBL2767111

Cl[Mn]Cl.c1cn(C(n2ccc(C34CC5CC(CC(C5)C3)C4)n2)n2ccc(C34CC5CC(CC(C5)C3)C4)n2)nc1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 2/20 0.40
HSD11B1 P28845 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GPR55 Q9Y2T6 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
GFER P55789 1/20 0.30
MAPT P10636 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butadiene SCHEMBL2765003 0.84 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AKDM4EHSD11B1
SCHEMBL2766280 0.77 KDM4E (0.38) ALDH1A1MEN1KMT2AKDM4EHSD11B1
SCHEMBL5029515 0.73 KDM4E (0.44) ALDH1A1MEN1KMT2AKDM4EHSD11B1
SCHEMBL2765827 0.71 KDM4E (0.38) ALDH1A1MEN1KMT2AKDM4EHSD11B1
SCHEMBL2767113 0.69 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AKDM4EHSD11B1
SCHEMBL31010376 0.65 KDM4E (0.36) ALDH1A1MEN1KMT2AKDM4EHSD11B1
SCHEMBL2765963 0.64 KDM4E (0.37) ALDH1A1MEN1KMT2AKDM4EHSD11B1
SCHEMBL2766782 0.64 LMNA (0.36) ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL2766635 0.62 CYP19A1 (0.37) ALDH1A1SMN1; SMN2LMNA
SCHEMBL31010265 0.61 EPHX2 (0.42) ALDH1A1MEN1KMT2AKDM4EHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266911-B1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL CO (JP) 2010-04-14 EP disclosed
US-6881802-B2 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-04-19 US disclosed
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-02-13 US disclosed
EP-1266911-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer BRAP, MCM4, BOLA2; BOLA2B ALDH1A1 3572/4885MEN1 632/4885KMT2A 1204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.