Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673102 | 0.83 | KDM4E (0.47) | RETKDM4EMAPTALKBH5FTO | |
| SCHEMBL3874031 | 0.81 | KDM4E (0.53) | RETKDM4EMAPTALKBH5FTO | |
| SCHEMBL27673143 | 0.80 | RET (0.60) | RETKDM4EMAPTALKBH5FTO | |
| SCHEMBL27653208 | 0.77 | RET (0.50) | RETKDM4EMAPTHSD17B10HSD11B1 | |
| SCHEMBL27653183 | 0.77 | RET (0.47) | RETKDM4EMAPTALKBH5FTO | |
| SCHEMBL28762588 | 0.76 | RET (0.51) | RETKDM4EMAPTALKBH5FTO | |
| SCHEMBL27653101 | 0.76 | RET (0.51) | RETKDM4EMAPTHSD17B10NQO2 | |
| SCHEMBL27673154 | 0.75 | RET (0.50) | RETKDM4EMAPTALKBH5FTO | |
| SCHEMBL27046198 | 0.73 | RET (0.57) | RETKDM4EMAPTALKBH5FTO | |
| SCHEMBL3877123 | 0.72 | KDM4E (0.56) | KDM4EMAPTALKBH5FTOHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |