Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673117 | 0.81 | POLB (0.40) | RETKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL27653158 | 0.80 | RET (0.45) | RETGPR3LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL27673141 | 0.80 | IDO1 (0.49) | HSP90AA1IDO1ALKBH5FTOGPR3 | |
| SCHEMBL28762588 | 0.80 | RET (0.51) | HSP90AA1IDO1RETALKBH5FTO | |
| SCHEMBL3883800 | 0.79 | ALKBH5 (0.51) | HSP90AA1IDO1ALKBH5FTOGPR3 | |
| SCHEMBL27653075 | 0.78 | RET (0.46) | HSP90AA1RETALKBH5FTOGPR3 | |
| SCHEMBL27046198 | 0.77 | RET (0.57) | RETALKBH5FTOGPR3LMNA | |
| SCHEMBL27673143 | 0.76 | RET (0.60) | HSP90AA1IDO1RETALKBH5FTO | |
| SCHEMBL27653183 | 0.76 | RET (0.47) | RETALKBH5FTOLMNAKMT2A | |
| SCHEMBL3875043 | 0.75 | ALKBH5 (0.55) | HSP90AA1IDO1ALKBH5FTOGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |