Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 3/20 | 0.41 |
| ▸ | CCND1 | P24385 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673112 | 0.94 | AHR (0.50) | AHRESR1ESR2MEN1POLB | |
| SCHEMBL17454769 | 0.87 | AHR (0.57) | AHRESR1ESR2ALDH1A1GPR3 | |
| SCHEMBL27673176 | 0.80 | AHR (0.52) | AHRMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL27653048 | 0.77 | ESR1 (0.56) | AHRESR1ESR2MEN1POLB | |
| SCHEMBL3878280 | 0.77 | AHR (0.61) | AHRALDH1A1GPR3HSD17B10CDK4 | |
| SCHEMBL3872832 | 0.76 | AHR (0.71) | AHRMEN1CASP6KMT2AALDH1A1 | |
| SCHEMBL27673122 | 0.75 | ESR1 (0.46) | ESR1ESR2MEN1POLBGAA | |
| SCHEMBL27673145 | 0.75 | CDK4 (0.47) | ESR1ESR2MEN1POLBGAA | |
| SCHEMBL27673115 | 0.74 | AHR (0.52) | AHRMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL15583192 | 0.74 | AHR (0.47) | AHRALDH1A1GPR3HSD17B10CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |