Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 0.47 |
| ▸ | CCND1 | P24385 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | WEE1 | P30291 | 7/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 7/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673147 | 0.81 | IMPDH2 (0.51) | CDK4CCND1WEE1CHEK1IMPDH2 | |
| SCHEMBL27653106 | 0.80 | IMPDH2 (0.58) | CDK4CCND1ESR1ESR2IMPDH2 | |
| SCHEMBL27673122 | 0.79 | ESR1 (0.46) | CDK4CCND1ESR1ESR2WEE1 | |
| SCHEMBL3886228 | 0.78 | IMPDH2 (0.59) | CDK4CCND1CHEK1IMPDH2IMPDH1 | |
| SCHEMBL28762584 | 0.78 | CDK4 (0.48) | CDK4CCND1ESR1ESR2WEE1 | |
| SCHEMBL27653233 | 0.78 | CDK4 (0.51) | CDK4CCND1ESR1ESR2WEE1 | |
| SCHEMBL27673105 | 0.75 | MEN1 (0.44) | CDK4CCND1ESR1ESR2WEE1 | |
| SCHEMBL27673174 | 0.75 | AHR (0.50) | CDK4CCND1ESR1ESR2WEE1 | |
| SCHEMBL27673112 | 0.75 | AHR (0.50) | CDK4CCND1ESR1ESR2WEE1 | |
| SCHEMBL3881310 | 0.74 | CDK4 (0.51) | CDK4CCND1IMPDH2IMPDH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |