SCHEMBL27673115

SCHEMBL27673115

Nc1cc2c(cc1-c1ccccc1O)[nH]c1ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.52
IMPDH2 P12268 1/20 0.45
IMPDH1 P20839 1/20 0.45
CHEK1 O14757 1/20 0.44
WEE1 P30291 1/20 0.44
ALDH1A1 P00352 3/20 0.44
GPR3 P46089 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KIF11 P52732 7/20 0.41
PARP1 P09874 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CDK4 P11802 1/20 0.41
CCND1 P24385 1/20 0.41
KDM4E B2RXH2 4/20 0.40
MAPT P10636 2/20 0.39
ATM Q13315 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27673176 0.94 AHR (0.52) AHRIMPDH2IMPDH1CHEK1WEE1
Carbazole SCHEMBL27571745 0.83 ALDH1A1 (0.64) AHRIMPDH2IMPDH1CHEK1WEE1
SCHEMBL3876929 0.82 AHR (0.61) AHRIMPDH2IMPDH1ALDH1A1GPR3
SCHEMBL27673112 0.80 AHR (0.50) AHRCHEK1WEE1ALDH1A1GPR3
SCHEMBL3878280 0.78 AHR (0.61) AHRIMPDH2IMPDH1ALDH1A1GPR3
SCHEMBL3872832 0.77 AHR (0.71) AHRALDH1A1GPR3HSD17B10KIF11
SCHEMBL17196500 0.76 AHR (0.52) AHRIMPDH2IMPDH1ALDH1A1GPR3
SCHEMBL27673174 0.74 AHR (0.50) AHRCHEK1WEE1ALDH1A1GPR3
SCHEMBL27673147 0.74 IMPDH2 (0.51) AHRIMPDH2IMPDH1CHEK1WEE1
SCHEMBL27673124 0.74 APP (0.44) IMPDH2IMPDH1CHEK1ALDH1A1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1937994-A Keratin dyeing compounds, keratin dyeing compositions containing them and their use PROCTER & GAMBLE (US) 2007-03-28 CN disclosed