O-Tolylamine

O-Tolylamine

SCHEMBL27673299

Cc1c(C(=O)O)cccc1C(=O)O.Cc1ccccc1N

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.58
HSD17B10 Q99714 4/20 0.58
NPC1 O15118 1/20 0.58
CASP3 P42574 1/20 0.58
RAB9A P51151 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
MYC P01106 2/20 0.58
CYP3A4 P08684 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
ALDH1A1 P00352 5/20 0.53
HPGD P15428 3/20 0.53
MMP2 P08253 1/20 0.53
CYP2C9 P11712 2/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
AKR1B10 O60218 1/20 0.51
TRPA1 O75762 1/20 0.51
ABCB11 O95342 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL412192 0.84 MMP2 (0.61) KDM4EHSD17B10NPC1CASP3RAB9A
SCHEMBL29622715 0.84 MMP2 (0.61) KDM4EHSD17B10NPC1CASP3RAB9A
Salicylic Acid SCHEMBL10362316 0.84 ALDH1A1 (0.64) KDM4EHSD17B10NPC1CASP3RAB9A
Hydrochloric Acid SCHEMBL10708599 0.82 MMP2 (0.59) KDM4EHSD17B10NPC1CASP3RAB9A
Hydrazine SCHEMBL28166056 0.82 TSHR (0.57) KDM4EHSD17B10NPC1CASP3RAB9A
SCHEMBL27703149 0.82 TSHR (0.61) KDM4EHSD17B10NPC1CASP3RAB9A
SCHEMBL756585 0.82 TSHR (0.61) KDM4EHSD17B10NPC1CASP3RAB9A
Benzene SCHEMBL27265959 0.82 TSHR (0.61) KDM4EHSD17B10NPC1CASP3RAB9A
SCHEMBL10434368 0.81 KDM4E (0.50) KDM4EHSD17B10NPC1CASP3RAB9A
SCHEMBL29357094 0.80 ALDH1A1 (0.65) KDM4EHSD17B10NPC1CASP3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-85102019-A Produce the technology of quinones by the arylamine oxidation 1985-11-10 CN disclosed