Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002526 | 0.78 | POLB (0.42) | POLBSMN1; SMN2TP53MAPT | |
| SCHEMBL27692473 | 0.76 | POLB (0.37) | POLBSMN1; SMN2TP53MAPT | |
| SCHEMBL19049304 | 0.73 | POLB (0.38) | POLBSMN1; SMN2TP53MAPT | |
| SCHEMBL3276082 | 0.72 | ALDH1A1 (0.41) | POLBSMN1; SMN2TP53MAPT | |
| SCHEMBL3274275 | 0.72 | POLB (0.37) | POLBSMN1; SMN2TP53MAPT | |
| SCHEMBL13384635 | 0.72 | KMT2A (0.44) | POLBSMN1; SMN2TP53MAPT | |
| SCHEMBL27259618 | 0.71 | ALDH1A1 (0.54) | SMN1; SMN2MAPT | |
| SCHEMBL9120822 | 0.69 | ALDH1A1 (0.50) | POLBSMN1; SMN2MAPT | |
| SCHEMBL9850884 | 0.68 | SMN1; SMN2 (0.36) | POLBSMN1; SMN2TP53MAPT | |
| SCHEMBL3274867 | 0.66 | ALDH1A1 (0.54) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006078-A | Gonadotropin releasing hormone receptor antagonists | WYETH CORP (US) | 2007-07-25 | — | — | CN | disclosed |