Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120822 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TSHRGAARAB9ASMN1; SMN2 | |
| SCHEMBL3274867 | 0.83 | ALDH1A1 (0.54) | ALDH1A1RXFP1TSHRCYP1A2RAB9A | |
| SCHEMBL9850884 | 0.75 | SMN1; SMN2 (0.36) | ALDH1A1TSHRCYP1A2GAACYP2C9 | |
| SCHEMBL19002526 | 0.74 | POLB (0.42) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2300954 | 0.74 | RAB9A (0.60) | ALDH1A1RXFP1GAARAB9ASMN1; SMN2 | |
| SCHEMBL9643824 | 0.73 | SMN1; SMN2 (0.36) | ALDH1A1TSHRGAACYP2C9RAB9A | |
| SCHEMBL3274275 | 0.72 | POLB (0.37) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL211358 | 0.71 | RXFP1 (0.50) | ALDH1A1RXFP1TSHRCYP1A2GAA | |
| SCHEMBL27673868 | 0.71 | POLB (0.39) | SMN1; SMN2MAPT | |
| SCHEMBL24271761 | 0.71 | ALDH1A1 (0.41) | ALDH1A1RXFP1CYP1A2GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026484-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026479-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |