Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 18/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 18/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264766 | 0.85 | NR1H2 (0.54) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL27654031 | 0.79 | NR1H2 (0.57) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124839 | 0.73 | NR1H2 (0.47) | NR1H2NR1H3PARP1 | |
| SCHEMBL29129467 | 0.72 | P2RX7 (0.44) | — | |
| SCHEMBL437574 | 0.71 | PARP1 (0.45) | NR1H2NR1H3PARP1 | |
| SCHEMBL1124136 | 0.70 | NR1H2 (0.54) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL995354 | 0.70 | NR1H2 (0.58) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL27446187 | 0.70 | USP2 (0.42) | NR1H2NR1H3PARP1USP2TP53 | |
| SCHEMBL1124642 | 0.70 | KMT2A (0.65) | NR1H2NR1H3USP2TP53MAPK1 | |
| SCHEMBL1126131 | 0.70 | NR1H2 (0.71) | NR1H2NR1H3PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914173-A | Quinolines useful in treating cardiovascular disease | WYETH CORP (US) | 2007-02-14 | — | — | CN | disclosed |