Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 8/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655269 | 0.81 | PDE4A (0.42) | GAAPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL2910790 | 0.81 | NPC1 (0.53) | NPC1CSNK2A1PDE4APDE4DPDE4B | |
| SCHEMBL92047 | 0.78 | GAA (1.00) | GAANPC1TSHRMEN1KMT2A | |
| SCHEMBL5951825 | 0.72 | GAA (0.78) | GAANPC1TSHRMAPT | |
| SCHEMBL2910658 | 0.72 | KMT2A (0.48) | GAAPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL27368676 | 0.72 | ALDH1A1 (0.58) | PDE4APDE4DPDE4BPDE4CTSHR | |
| SCHEMBL24928857 | 0.72 | CSNK2A1 (0.42) | CSNK2A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7683050 | 0.72 | CSNK2A1 (0.49) | NPC1CSNK2A1 | |
| SCHEMBL30845563 | 0.72 | CSNK2A1 (0.42) | CSNK2A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL24928888 | 0.72 | CSNK2A1 (0.42) | CSNK2A1PDE4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922144-A | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs | MEMORY PHARM CORP (US) | 2007-02-28 | — | — | CN | disclosed |