SCHEMBL7683050

SCHEMBL7683050

Nc1cc(OC2CCCC2)c(Cl)cc1F

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.49
PPOX P50336 2/20 0.47
SCN9A Q15858 11/20 0.46
HPGD P15428 1/20 0.36
KMO O15229 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8088011 0.98 SCN9A (0.48) CSNK2A1PPOXSCN9AHPGDKMO
Hydrochloric Acid SCHEMBL8369025 0.98 CSNK2A1 (0.50) CSNK2A1PPOXSCN9AHPGDKMO
SCHEMBL8599165 0.93 CSNK2A1 (0.41) CSNK2A1PPOXSCN9ANPC1
SCHEMBL8206326 0.83 SCN9A (0.46) CSNK2A1PPOXSCN9ANPC1RAB9A
SCHEMBL9562757 0.82 KMO (0.36) CSNK2A1PPOXSCN9AKMONPC1
SCHEMBL8084589 0.80 MCHR1 (0.41) CSNK2A1PPOXSCN9ANPC1
SCHEMBL2904851 0.79 PDE4A (0.46)
SCHEMBL8602564 0.78 NPC1 (0.38) CSNK2A1PPOXSCN9AHPGDNPC1
SCHEMBL8076457 0.77 MCHR1 (0.39) PPOXSCN9ANPC1
SCHEMBL30340313 0.77 NPC1 (0.53) CSNK2A1SCN9AKMONPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6092913-A None JP disclosed
US-6444615-B1 COMPOUNDS EFFECTIVE AS PREEMERGENT AND POSTEMERGENT HERBICIDES DOW AGROSCIENCES LLC 2002-09-03 US disclosed
EP-1157991-A2 Herbicidal imidazolidinetrione and thioxo-imidazolidinediones Dow AgroSciences LLC (US) 2001-11-28 EP disclosed
EP-0493606-B1 HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEM RES (JP) 2000-10-18 EP disclosed
EP-1006105-A1 Benzene derivatives SAGAMI CHEMICAL RESEARCH CENTER (JP) 2000-06-07 EP disclosed
EP-0659735-B1 PROCESS FOR PRODUCING ANILINE DERIVATIVE SAGAMI CHEM RES (JP) 1999-01-13 EP disclosed
EP-0626370-B1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL CO (JP) 1998-02-11 EP disclosed
CN-1036564-C Herbicidal glutarmides ROHM & HAAS (US) 1997-12-03 CN disclosed
US-5639915-A Process for the production of aniline derivatives SAGAMI CHEMICAL RESEARCH CENTER (JP) 1997-06-17 US disclosed
EP-0635485-B1 TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEM RES (JP) 1997-06-11 EP disclosed
JP-H0692913-A PRODUCTION OF ANILINE DERIVATIVE SAGAMI CHEM RES CENTER 1994-04-05 JP disclosed
US-5281742-A Bis(fluorophenyl) carbonate derivatives SAGAMI CHEMICAL RESEARCH CENTER (JP) 1994-01-25 US disclosed
EP-0415641-B1 Substituted glutaramic acids and derivatives ROHM & HAAS (US) 1994-01-19 EP disclosed
US-5238908-A HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES ROHM AND HAAS COMPANY (US) 1993-08-24 US disclosed
EP-0496347-A2 Methods of preparing fluorobenzene derivatives and related compounds SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-07-29 EP disclosed
EP-0493606-A1 HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-07-08 EP disclosed
CN-1049846-A Glutarimide with weeding activity ROHM & HAAS (US) 1991-03-13 CN disclosed
CN-1049770-A Weeding glutaramic acid and its derivative ROHM & HAAS (US) 1991-03-13 CN disclosed
EP-0415641-A1 Substituted glutaramic acids and derivatives ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed
EP-0415642-A1 Glutarimides ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed