SCHEMBL27675306

SCHEMBL27675306

OCC1(CO)CN(Cc2ccccc2)C1.OCC1(CO)CN(Cc2ccccc2)C1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.54
GAA P10253 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
TSHR P16473 1/20 0.53
POLB P06746 4/20 0.51
ALDH1A1 P00352 2/20 0.51
OPRL1 P41146 1/20 0.47
FUCA1 P04066 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP3A4 P08684 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MC4R P32245 1/20 0.46
OPRM1 P35372 1/20 0.46
OPRD1 P41143 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3579844 1.00 SIGMAR1 (0.54) SIGMAR1GAAMEN1KMT2ATSHR
SCHEMBL10755612 0.91 MEN1 (0.50) SIGMAR1GAAMEN1KMT2ATSHR
SCHEMBL9233103 0.85 POLB (0.58) SIGMAR1GAAMEN1KMT2APOLB
SCHEMBL14626231 0.84 SIGMAR1 (0.54) SIGMAR1GAAMEN1KMT2ATSHR
SCHEMBL28911881 0.83 ALDH1A1 (0.68) GAAMEN1KMT2APOLBALDH1A1
SCHEMBL19463296 0.81 GAA (0.59) SIGMAR1GAAMEN1KMT2ATSHR
SCHEMBL19463297 0.81 GAA (0.59) SIGMAR1GAAMEN1KMT2ATSHR
SCHEMBL18123311 0.81 POLB (0.65) SIGMAR1GAAMEN1KMT2ATSHR
SCHEMBL19779269 0.80 POLB (0.55) GAAMEN1KMT2ATSHRPOLB
SCHEMBL28119006 0.80 GAA (0.58) SIGMAR1GAAMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-86106702-A The preparation method of azepine-3-cyclobutane-carboxylic acid and salt thereof 1987-04-01 CN disclosed