Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16597339 | 0.91 | SORD (0.56) | SORDGPBAR1GPR119PDE10ALRRK2 | |
| SCHEMBL26972630 | 0.85 | GPR119 (0.44) | SORDGPBAR1GPR119MAP4K4CYP2D6 | |
| SCHEMBL26972637 | 0.85 | GPR119 (0.44) | SORDGPBAR1GPR119MAP4K4CYP2D6 | |
| Hydrochloric Acid SCHEMBL27675481 | 0.84 | GPBAR1 (0.44) | SORDGPBAR1GPR119MAP4K4CYP2D6 | |
| SCHEMBL10569035 | 0.82 | MAP4K4 (0.46) | SORDGPBAR1GPR119MAP4K4CYP2D6 | |
| SCHEMBL2146619 | 0.80 | PLD1 (0.50) | SORDPDE10AGRM1 | |
| SCHEMBL2146610 | 0.80 | PLD1 (0.50) | SORDPDE10AGRM1 | |
| SCHEMBL2146736 | 0.80 | PLD1 (0.50) | SORDPDE10AGRM1 | |
| SCHEMBL24929586 | 0.80 | GPR119 (0.47) | SORDGPBAR1GPR119CYP2D6DPP4 | |
| SCHEMBL30775215 | 0.80 | GPR119 (0.47) | SORDGPBAR1GPR119CYP2D6DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-86102398-A | The preparation method of substituted benzimidazole derivative | — | 1986-11-12 | — | — | CN | disclosed |