Styrene

Styrene

SCHEMBL27675379

C=COC(C)=O.C=Cc1ccccc1.C=Cc1ccccc1C=C

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
TSHR P16473 2/20 0.47
AKR1C3 P42330 1/20 0.38
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HTT P42858 1/20 0.36
KMT2A Q03164 3/20 0.33
RECQL P46063 1/20 0.33
MEN1 O00255 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTGS2 P35354 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33
TUBB2A Q13885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9640408 0.93 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL381689 0.93 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL28187565 0.93 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL10608565 0.91 ALDH1A1 (0.52) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL21448340 0.91 ALDH1A1 (0.52) ALDH1A1TSHRAKR1C3GLATDP1
SCHEMBL27995843 0.91 ALDH1A1 (0.39) ALDH1A1KMT2AMEN1KDM4ECYP2C19
SCHEMBL28215138 0.91 PTGS2 (0.39) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL8098448 0.90 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL23462407 0.88 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL3419207 0.88 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3GLATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-86101723-B Preparation method of uniform polymer microspheres for liquid chromatography 中国科学院化学研究所 1987-12-09 CN disclosed