Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1631549 | 0.90 | NPBWR1 (0.41) | PTGER1PDE10AALDH1A1MAPTNPSR1 | |
| SCHEMBL1628962 | 0.84 | MAPK14 (0.42) | PDE10ALMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL1629555 | 0.83 | PDE10A (0.48) | PTGER1PDE10ALMNAALDH1A1MAPT | |
| SCHEMBL1629204 | 0.74 | KDM4E (0.39) | LMNAALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL1630525 | 0.74 | HSP90AA1 (0.44) | PDE10ALMNAALDH1A1HSP90AA1 | |
| SCHEMBL1219068 | 0.73 | HSP90AA1 (0.45) | PDE10ALMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL1631623 | 0.73 | P2RX7 (0.42) | MAPTHSP90AA1 | |
| SCHEMBL12722862 | 0.72 | HSP90AA1 (0.47) | PTGER1PDE10AALDH1A1MAPTHSP90AA1 | |
| SCHEMBL1629564 | 0.72 | HSP90AA1 (0.44) | PDE10AALDH1A1MAPTHSP90AA1 | |
| SCHEMBL1631531 | 0.72 | HSP90AA1 (0.62) | PDE10AMAPTHSP90AA1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006061-A | 1,5-diphenylpyrazoles | MERCK PATENT GMBH (DE) | 2007-07-25 | — | — | CN | disclosed |