Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655593 | 0.90 | ESR1 (0.49) | ESR1LMNAMEN1ALDH1A1MAPT | |
| SCHEMBL27675452 | 0.86 | PDE4A (0.48) | ESR1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL27655448 | 0.84 | ESR1 (0.43) | ESR1LMNAMEN1ALDH1A1GAA | |
| SCHEMBL27675509 | 0.84 | GAA (0.48) | LMNAALDH1A1GAA | |
| SCHEMBL27655553 | 0.82 | KDM4E (0.40) | LMNAALDH1A1 | |
| SCHEMBL27675558 | 0.82 | ESR1 (0.46) | ESR1 | |
| SCHEMBL27655658 | 0.76 | ICAM1 (0.53) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL27675416 | 0.76 | ACHE (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5130016 | 0.74 | ESR1 (0.77) | ESR1 | |
| SCHEMBL27655527 | 0.74 | KDM4E (0.52) | LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |